Researchers at Nagaland University have discovered Sinapic acid, a naturally occurring compound in edible plants, as a promising agent for diabetic wound healing, particularly for diabetic foot ulcers. This breakthrough could help reduce severe complications such as infections and amputations.
Sinapic acid works by activating the SIRT1 pathway, which is essential for tissue repair, angiogenesis, and inflammation control. Diabetic wounds often heal slowly due to poor blood circulation and neuropathy, but the compound’s antioxidant properties significantly accelerate the healing process.
The study, published in Nature Scientific Reports, found that oral administration of Sinapic acid promotes wound repair in preclinical models. Interestingly, a lower dose of 20 mg/kg was more effective than a higher dose, providing important guidance for future clinical applications.
This discovery offers a natural, safe, and effective alternative to synthetic drugs, potentially making diabetic wound management more accessible and affordable, especially in resource-limited settings.
