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Top 10 Deadliest Pandemics in Human History

Pandemics have shaped human history, bringing widespread suffering and altering societies. From the Black Death to COVID-19, these outbreaks remind us of humanity’s vulnerability to disease.

Top 10 Deadliest Pandemics

  1. Black Death (1346–1353) – 75–200 million deaths.
  2. HIV/AIDS (1976–Present) – 36 million deaths.
  3. Spanish Flu (1918–1920) – 20–50 million deaths.
  4. Plague of Justinian (541–542 AD) – 25 million deaths.
  5. COVID-19 (2020–Present) – 21 million deaths.
  6. Antonine Plague (165 AD) – 5 million deaths.
  7. Asian Flu (1956–1958) – 2 million deaths.
  8. Third Cholera Pandemic (1852–1860) – 1 million deaths.
  9. Russian Flu (1889–1890) – 1 million deaths.
  10. Hong Kong Flu (1968–1969) – 1 million deaths.

Highlights of Major Pandemics

  • Black Death: Wiped out up to 60% of Europe’s population.
  • HIV/AIDS: Still ongoing, managed through antiretroviral therapy.
  • Spanish Flu: Infected 500 million people during WWI.
  • Justinian Plague: Weakened the Byzantine Empire.
  • COVID-19: Changed global health, economy, and daily life.

Takeaway

Pandemics are not just medical events—they reshape economies, societies, and cultures. Learning from the past helps humanity prepare for the future.

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